CRISPR technology has rapidly advanced in recent years, with new tools and clinical breakthroughs. Highlight the recent developments in CRISPR-based gene editing technology applications. Discuss the opportunities and ethical challenges these advancements present for healthcare and society.

CRISPR technology has emerged major technological breakthrough in Biotechnology, advancing gene editing and gene sequencing method. Recent developments in CRISPR based gene editing technology applicability: I CRISPR based gene technology to address cancer disease in lucid II utilizing in xenotransplantation - rectly in using pig hosts to human body (3) Addressing genetic disorders - Alzheimer penduity x OK - promoting CRISPR let Alzheimer preventia

F multi-pronged → gene editing tool applicability for addressing mitochondria disease. Step to adding genetic default in body S Editing - utilizing for designer baby Need technology-advance: ex gene editing for cancer treatment advancing biotechnology (India's Bio Economy $175 2011 Loop) Opportunities: → Case of hung → help in fighting lung peravaent disease - HIV/cancers etc Gene therapy helps to addin grafti disease Protecting genetic alteration → Recent re-extinction attempt on cooll

Ethical challenges: I Against Humanity and Bio-ethics: ex China's designer baby to make superhumam (2) Misuse of technology → some narrow interest ex BIG terrorism (3) Lack of regulatory mechanism (4) Chaos of pandemic emergence (5) Against natural races → biological weaponry → agent natural Way forward: I Global Convention on ethical outlines of CRISPR technology (2) India should set up COF on CRISPR (3) Industry-academia-govt collaboration CRISPER technology is major leap forward in advancement of Biotechnology.

— Vipulbhai Karmanbhai Chaudhary · AIR 115